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However, it is difficult to translate preclinical outcomes into clinical practice because it is still unclear whether the mechanisms observed in rodent models have clinical relevance ( in vivo validation in rodents

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

The simultaneous interaction with the endogenous Ub-E2-E3 complex and the protein of interest results in the generation of an Ub-E2-E3-neosubstrate complex, ultimately leading to ubiquitinylation and degradation of target protein

Polyphenols are natural bioactive compounds, mostly from herbs, fruits, vegetables and medicinal plants